MUSCLE INVOLVEMENT IN AMYOTROPHIC LATERAL SCLEROSIS: UNDERSTANDING THE PATHOGENESIS AND ADVANCING THERAPEUTICS

Muscle Involvement in Amyotrophic Lateral Sclerosis: Understanding the Pathogenesis and Advancing Therapeutics

Amyotrophic lateral sclerosis (ALS) is a fatal condition characterized by the selective loss of motor neurons in the motor cortex, brainstem, and spinal cord.Muscle involvement, muscle atrophy, and subsequent paralysis are among the main features of this disease, which is defined as a neuromuscular disorder.ALS is a persistently progressive disease

read more



Precision Low-Cost Compact Micro-Displacement Sensors Based on a New Arrangement of Cascaded Levers with Flexural Joints

Existing displacement sensors of micrometers to sub-micron precision are expensive and have various limitations.This paper reports the design and development of a new contact type compact micro-displacement sensor of sub-micron precision for a fraction of the cost of commercial devices.The basic concept of the Bolero new sensor system applies a mec

read more